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PREVENTION AGAISNT
MALARIA, DENGUE, ZIKA, CHIKUNGUNYA AND OTHER INSECT BORNE DISEASES
Nanofor® is an insect repellent solution, for application on textiles, surfaces and skin, with the active substance IR3535® and efficacy enhanced by Sil2U® patented technology, acting in the prevention of vector-borne diseases, such as Malaria, Dengue, Zika fever, West Nile fever, Yellow fever, Chikungunya, Encephalitis, to name a few, transmitted by tropical mosquito species such as anopheles, aedes and culex and by ticks.
Conceived in commitment to the WHO’s “Global Vector Control Response (GVCR) 2017–2030” to prevent disease and respond to outbreaks and developed to achieve the Sustainable Development Goals and Universal Health Coverage.
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KEY FACTS
Vector-borne diseases account for more than 17% of all infectious diseases, causing more than 700 000 deaths annually. They can be caused by either parasites, bacteria or viruses.
Malaria is a parasitic infection transmitted by Anopheline mosquitoes. It causes an estimated 219 million cases globally, and results in more than 400,000 deaths every year. Most of the deaths occur in children under the age of 5 years.
Dengue is the most prevalent viral infection transmitted by Aedes mosquitoes. More than 3.9 billion people in over 129 countries are at risk of contracting dengue, with an estimated 96 million symptomatic cases and an estimated 40.000 deaths every year.
Other viral diseases transmitted by vectors include chikungunya fever, Zika virus fever, yellow fever, West Nile fever, Japanese encephalitis (all transmitted by mosquitoes), tick-borne encephalitis (transmitted by ticks).
Many of vector-borne diseases are preventable, through protective measures, and community mobilisation.
RECOMMENDATIONS
Reducing the use of pesticides and insecticides is increasingly the recommendation for the future.
The benefits are substantial in addressing climate, health, food system integrity, biodiversity, and a host of other problems caused by these chemicals.
OUR GLOBAL GOALS
ACTIVE SUBSTANCE
It’s a powerful and well tolerated active substance for insect repellency, the molecule is inspired by a naturally occurring amino acid. Beyond its proven efficacy, it has an excellent safety profile, friendly to humans, animals and the environment. Not toxic to aquatic organisms, such as fish or algae, and does not accumulate in the environment. Allows safe protection. Highly tolerable even for small children.
IR3535® is recommended as a safe and effective insect repellent by WHO (World Health Organization), ECHA (European Chemicals Agency), CDC (Centers for Disease Control) and EPA (Environmental Protection Agency).
MAIN CHARACTERISTICS OF THE ACTIVE SUBSTANCE
Mode of action is based on the olfactory effect
Insects avoid entering/landing in spaces with the active substance
There is no time delay
The active substance is a repellent, it as no killing action, no resistance can be developed.
It’s an innovative formulation and process for the preparation and fixation of insect repellent active substance (IR3535®) on textile substrate and other materials (surfaces) through silica particles, which stabilize the active principle inside, protecting it from environmental degradation and increasing their durability in materials, ensuring efficiency of repellency providing high and long lasting protection against vector mosquitoes of Malaria, Dengue, Zika, Chikungunya and other insect borne diseases.
silica particles
Sil2U® grants properties to several materials, through the use of particles, which work as a carrier for the active agents, attaching them to the substrates.
durability
ENHANCES the durability of the active substances on the materials.
PROTECTS active substances from environmental degradation.
repellence efficacy / diseases
repellence efficacy / diseases
mosquitoes
Anopheles gambiae
Malaria
aedes aegypti and albopictus
Dengue, Zika, Chikungunya and Yellow Fever
Culex spp.
West Nile Virus and Encephalitis
ticks / chiggers
Ixodes and Amblyomma spp
Lyme disease, Ehrlichioses, Tularemia
biting flies
Like deer , black and stable flies
Fly fever, Bartonellosis and Leischmaniasis
head lice
Cause intense itching and irritation, allergies and infections
wasps / bees
The bite can induce adverse reactions, ranging from localized pain and swelling, to potentially fatal conditions
VECTORS CAN CAUSE NUMEROUS DISEASES IN HUMANS
RISK
80% of the world’s population is at risk of one or more vector-borne disease
burden
17% of the global burden of communicable diseases is due to vector-borne diseases
MORTALITY
Over 700 000 deaths are caused by vector-borne diseases annually
Vector-borne diseases pose a major threat to the health of societies around the world. They are caused by parasites, viruses and bacteria transmitted to humans by mosquitoes, sandflies, triatomine bugs, blackflies, ticks, tsetse flies, mites, snails and lice. The major global vector-borne diseases of humans include malaria, dengue, lymphatic filariasis, schistosomiasis, chikungunya, onchocerciasis, Chagas disease, leishmaniasis, Zika virus disease, yellow fever and Japanese encephalitis. Other vector-borne diseases, such as human African trypanosomiasis, Lyme disease, tick-borne encephalitis and West Nile fever, are of local importance in specific areas or populations. The major vector-borne diseases together account for around 17% of the estimated global burden of communicable diseases and claim more than 700 000 lives every year. The burden is highest in tropical and subtropical areas. More than 80% of the global population live in areas at risk from at least one major vector-borne disease, with more than half at risk from two or more. The risk of infection for certain viral pathogens is particularly high in towns and cities where Aedes and Culex mosquitoes proliferate because of favourable habitats and close contact with human beings. Morbidity and mortality rates are often disproportionately high in poorer populations. People who survive these diseases can be left permanently disabled or disfigured, compounding their disadvantage. Vector-borne diseases exact an immense toll on economies and restrict both rural and urban development.
Impressive gains have been made against malaria, onchocerciasis, lymphatic filariasis and Chagas disease, but the burden of many other vector-borne diseases has increased in recent years. Since 2014, major outbreaks of dengue, malaria, chikungunya and yellow fever have afflicted populations, claimed lives and overwhelmed health systems in many countries. Zika virus infections and their associated complications rapidly spread across the WHO Region of the Americas and beyond in 2016, affecting individuals and families and causing social and economic disruption. Social, demographic and environmental factors have altered pathogen transmission patterns, resulting in intensification, geographical spread, re-emergence or extension of transmission seasons. In particular, unplanned urbanization, lack of reliable piped water supply and inadequate solid waste or excreta management can render large populations in towns and cities at risk of viral diseases spread by mosquitoes. Increased global travel and trade, combined with environmental factors such as altered land use patterns (e.g. deforestation) and climate change, may also have an effect. Together, such factors influence the reach of vector populations and the transmission patterns of disease-causing pathogens. The dynamic and complex nature of vector-borne pathogens complicates predictions of the impact of existing, re-emerging or new diseases on human health. Despite this unpredictability, it is reasonable to expect emergence of some new vector-borne diseases and further intensification of others, particularly those viral diseases transmitted by Aedes mosquitoes that are closely associated with urbanization. Also of concern are pathogens that may be transmitted by Culex mosquito species and other arthropods. This complexity and unpredictability underscores the critical need for adaptive and sustained approaches to prevent and reduce pathogen transmission to reduce disease burden.
(In Global Vector Control Response (GVCR) 2017–2030, WHO fact sheet on vector-borne diseases)
EUROPEAN REGULATORY COMPLIANCE
WHAT IS THE PURPOSE OF BIOCIDAL PRODUCTS REGULATION?
The purpose of BPR (Regulation (EU) No 528/2012) is to improve the functioning of the internal market through the harmonisation of the rules on the making available on the market and the use of biocidal products, whilst ensuring a high level of protection of both human and animal health and the environment. The provisions of this Regulation are underpinned by the precautionary principle, the aim of which is to safeguard the health of humans, the health of animals and the environment. Particular attention shall be paid to the protection of vulnerable groups.
WHAT IS THE DEFINITION OF BIOCIDAL PRODUCTS?
(according to item a), of Article 3, of BPR)
‘biocidal product’ means
- Any substance or mixture, in the form in which it is supplied to the user, consisting of, containing or generating one or more active substances, with the intention of destroying, deterring, rendering harmless, preventing the action of, or otherwise exerting a controlling effect on, any harmful organism by any means other than mere physical or mechanical action,
- any substance or mixture, generated from substances or mixtures which do not themselves fall under the first indent, to be used with the intention of destroying, deterring, rendering harmless, preventing the action of, or otherwise exerting a controlling effect on, any harmful organism by any means other than mere physical or mechanical action.
A treated article that has a primary biocidal function shall be considered a biocidal product.
Authorisations: European Chemical Agency Link: (https://echa.europa.eu/information-on-chemicals/biocidal-products/-/disbp/factsheet/NL-0015633-0000/authorisationid); Federal Office for Chemicals (BfC) at BAuA (Germany); DGS – Direção Geral da Saúde (Portugal); ANSES – Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et dutravail (France); Dirección General de Salud Pública, Calidad e Innovación (Spain); Board for the Authorisation of Plant Protection Products and Biocides (Ctgb, The Netherlands); Health and Safety Executive (Great Britain and Northern Ireland).
anti-insect spray for textile
anti-insect spray for textile
1
Shake bottle several times before use.
2
The spray should be applied, in well ventilated space, with the bottle vertically and at 15 cm distance from the clothing.
3
Spray to evenly homogenize the textile (1.6 ml of product per square meter – equivalent to 5.43 ± 0.5 g of IR3535®).
4
Dry your clothes completely before wearing.
5
Re-apply whenever the textile gets wet (from rain or swimming, e.g.), after 3 months or after 1 domestic laundry cycle – for tropical mosquitoes – and after 1 month or after 3 domestic laundry cycle – for ticks – to ensure the repellent efficacy.
anti-insect spray for textile / conversion
ADDITIVE PLUS for surfaces
ADDITIVE PLUS for surfaces
1
Mix the additive bottle before use.
2
Slowly dilute 50 ml of the additive with 950 ml of clean water, to get a liter of ready to use solution (5% of additive per liter of diluted solution).
3
Mix well until homogenization.
4
Pulverize the surfaces using a sprayer, to evenly humidify the surfaces. 1000 ml is enough to treat a surface of 20 square meters.
5
For full outdoor effectiveness, re-apply the product whenever there is a risk of deterioration due to environmental factors (rain, wind, high temperature).
ADDITIVE PLUS for surfaces
ADDITIVE PLUS for surfaces / conversion
NANOFOR PLUS (2in1) for textile+skin
Textile: Follow the instructions for anti-insect spray textile
Skin: For effective protection, apply the product to all uncovered parts of the body, at a distance of 10 to 15 cm. On the face, spray the product in the palm of the hand and apply avoiding contact with the eyes and mouth. Renew the application at least every 8 hours and in case of intense activity, every 6 hours. Reapply after bathing or showering. Do not apply to children under 2 (two) years.
STAY SAFE
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